10X single cell sequencing of HNT34 cocultured with Tcells with or without antibody targeting SLAMF6
This dataset contains fastq-files from single cell 5’ RNA sequencing of the AML cell line HNT34 and normal T cells following co-culture with and without an antibody blocking SLAMF6 (TNC-1). The libraries were prepared using 10X GEM-X Universal 5’ Gene Expression v3 Reagent Kit. In total, the dataset contains sequenced gene expression libraries from four samples (HNT34 co-cultured with T cells from two different donors; for both donors there is one sample with and one sample without the blocking antibody).
This dataset is 1 of 1 included in the study titled Aberrant expression of SLAMF6 constitutes a targetable immune escape mechanism in acute myeloid leukemia, http://identifiers.org/ega.study:EGAS50000001085.
Official landing page: http://identifiers.org/ega.dataset:EGAD50000001573